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Integrate multiple traits to detect novel trait–gene association using GWAS summary data with an adaptive test approach

MOTIVATION: Genetics hold great promise to precision medicine by tailoring treatment to the individual patient based on their genetic profiles. Toward this goal, many large-scale genome-wide association studies (GWAS) have been performed in the last decade to identify genetic variants associated wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformatics
Hauptverfasser: Guo, Bin, Wu, Baolin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596889/
https://ncbi.nlm.nih.gov/pubmed/30476000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty961
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