CK2 Oppositely Modulates l-DOPA-Induced Dyskinesia via Striatal Projection Neurons Expressing D1 or D2 Receptors

We have previously shown that casein kinase 2 (CK2) negatively regulates dopamine D1 and adenosine A(2A) receptor signaling in the striatum. Ablation of CK2 in D1 receptor-positive striatal neurons caused enhanced locomotion and exploration at baseline, whereas CK2 ablation in D2 receptor-positive n...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Cortés, Marisol, Malave, Lauren, Castello, Julia, Flajolet, Marc, Cenci, M. Angela, Friedman, Eitan, Rebholz, Heike
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596830/
https://ncbi.nlm.nih.gov/pubmed/29097596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0443-17.2017
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