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CK2 Oppositely Modulates l-DOPA-Induced Dyskinesia via Striatal Projection Neurons Expressing D1 or D2 Receptors
We have previously shown that casein kinase 2 (CK2) negatively regulates dopamine D1 and adenosine A(2A) receptor signaling in the striatum. Ablation of CK2 in D1 receptor-positive striatal neurons caused enhanced locomotion and exploration at baseline, whereas CK2 ablation in D2 receptor-positive n...
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| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6596830/ https://ncbi.nlm.nih.gov/pubmed/29097596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0443-17.2017 |
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