Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin

The secreted glycoprotein Reelin regulates embryonic brain development and adult brain functions. It has been suggested that reduced Reelin activity contributes to the pathogenesis of several neuropsychiatric and neurodegenerative disorders, such as schizophrenia and Alzheimer's disease; howeve...

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Publicat a:J Neurosci
Autors principals: Ogino, Himari, Hisanaga, Arisa, Kohno, Takao, Kondo, Yuta, Okumura, Kyoko, Kamei, Takana, Sato, Tempei, Asahara, Hiroshi, Tsuiji, Hitomi, Fukata, Masaki, Hattori, Mitsuharu
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596773/
https://ncbi.nlm.nih.gov/pubmed/28213441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3632-16.2017
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