Respiration-Deficient Astrocytes Survive As Glycolytic Cells In Vivo

Neurons and glial cells exchange energy-rich metabolites and it has been suggested, originally based on in vitro data, that astrocytes provide lactate to glutamatergic synapses (“lactate shuttle”). Here, we have studied astrocytes that lack mitochondrial respiration in vitro and in vivo. A novel mou...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Supplie, Lotti M., Düking, Tim, Campbell, Graham, Diaz, Francisca, Moraes, Carlos T., Götz, Magdalena, Hamprecht, Bernd, Boretius, Susann, Mahad, Don, Nave, Klaus-Armin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596567/
https://ncbi.nlm.nih.gov/pubmed/28314814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0756-16.2017
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