Respiration-Deficient Astrocytes Survive As Glycolytic Cells In Vivo

Neurons and glial cells exchange energy-rich metabolites and it has been suggested, originally based on in vitro data, that astrocytes provide lactate to glutamatergic synapses (“lactate shuttle”). Here, we have studied astrocytes that lack mitochondrial respiration in vitro and in vivo. A novel mou...

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Vydáno v:J Neurosci
Hlavní autoři: Supplie, Lotti M., Düking, Tim, Campbell, Graham, Diaz, Francisca, Moraes, Carlos T., Götz, Magdalena, Hamprecht, Bernd, Boretius, Susann, Mahad, Don, Nave, Klaus-Armin
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596567/
https://ncbi.nlm.nih.gov/pubmed/28314814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0756-16.2017
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