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Aminopyrimidine–galactose hybrids are highly selective galectin-3 inhibitors

Galectins are a family of carbohydrate recognition proteins involved in, among other things, modulating cell signalling and cell–environment interactions, giving them roles in several pathologies like cancer and idiopathic lung fibrosis. Hence, developing new galectin inhibitors with high affinity a...

詳細記述

保存先:
書誌詳細
出版年:Medchemcomm
主要な著者: Dahlqvist, Alexander, Zetterberg, Fredrik R., Leffler, Hakon, Nilsson, Ulf J.
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596385/
https://ncbi.nlm.nih.gov/pubmed/31303989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00183b
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