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Aminopyrimidine–galactose hybrids are highly selective galectin-3 inhibitors
Galectins are a family of carbohydrate recognition proteins involved in, among other things, modulating cell signalling and cell–environment interactions, giving them roles in several pathologies like cancer and idiopathic lung fibrosis. Hence, developing new galectin inhibitors with high affinity a...
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| Publicado no: | Medchemcomm |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6596385/ https://ncbi.nlm.nih.gov/pubmed/31303989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00183b |
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