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Separation of β-Amyloid Tryptic Peptide Species with Isomerized and Racemized L-Aspartic Residues with Ion Mobility in Structures for Lossless Ion Manipulations
Accumulation of β-amyloid (Aβ) is one of the hallmarks of Alzheimer’s disease. The deposition of β-amyloid plaques is likely to start years in advance of manifestation of clinical symptoms, although the exact timing is unknown. Over the years, Aβ peptides undergo both post-translational modification...
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| Veröffentlicht in: | Anal Chem |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6596305/ https://ncbi.nlm.nih.gov/pubmed/30816701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b04696 |
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