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Dnmt3a2 in the Nucleus Accumbens Shell Is Required for Reinstatement of Cocaine Seeking

Epigenetic mechanisms have gained increasing attention as regulators of synaptic plasticity and responsiveness to drugs of abuse. In particular, it has been shown that the activity of the DNA methyltransferase 3a (Dnmt3a) mediates certain long-lasting effects of cocaine. Here we examined the role of...

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Pubblicato in:J Neurosci
Autori principali: Cannella, Nazzareno, Oliveira, Ana M.M., Hemstedt, Thekla, Lissek, Thomas, Buechler, Elena, Bading, Hilmar, Spanagel, Rainer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596133/
https://ncbi.nlm.nih.gov/pubmed/30030395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0600-18.2018
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