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Dnmt3a2 in the Nucleus Accumbens Shell Is Required for Reinstatement of Cocaine Seeking

Epigenetic mechanisms have gained increasing attention as regulators of synaptic plasticity and responsiveness to drugs of abuse. In particular, it has been shown that the activity of the DNA methyltransferase 3a (Dnmt3a) mediates certain long-lasting effects of cocaine. Here we examined the role of...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cannella, Nazzareno, Oliveira, Ana M.M., Hemstedt, Thekla, Lissek, Thomas, Buechler, Elena, Bading, Hilmar, Spanagel, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596133/
https://ncbi.nlm.nih.gov/pubmed/30030395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0600-18.2018
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