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Stereoselective semi-synthesis of the neuroprotective natural product, serofendic acid
We have recently demonstrated a synthetic biology-enabled semi-synthesis of the potent neuroprotective compound, serofendic acid. An engineered bacterium produces ent-atis-16-en-19-oic acid, which has six of eight chiral carbons configured with the appropriate stereochemistry. Setting the configurat...
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| 出版年: | Medchemcomm |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Royal Society of Chemistry
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6595966/ https://ncbi.nlm.nih.gov/pubmed/31303993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00145j |
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