Relevance of CYP2B6 and CYP2D6 genotypes to methadone pharmacokinetics and response in the OPAL study

AIMS: Our study aimed to evaluate the impacts of the cytochrome P450 (CYP) 2B6‐G516T and CYP2D6 genetic polymorphisms on pharmacokinetic and clinical parameters in patients receiving methadone maintenance treatment. METHODS: Opioid PhArmacoLogy (OPAL) was a clinical survey of the sociodemographic ch...

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Detalles Bibliográficos
Publicado en:Br J Clin Pharmacol
Main Authors: Victorri‐Vigneau, Caroline, Verstuyft, Céline, Bouquié, Régis, Laforgue, Edouard‐Jules, Hardouin, Jean‐Benoit, Leboucher, Juliette, Le Geay, Bertrand, Dano, Corine, Challet‐Bouju, Gaëlle, Grall‐Bronnec, Marie
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595468/
https://ncbi.nlm.nih.gov/pubmed/30907440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13936
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