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Relevance of CYP2B6 and CYP2D6 genotypes to methadone pharmacokinetics and response in the OPAL study
AIMS: Our study aimed to evaluate the impacts of the cytochrome P450 (CYP) 2B6‐G516T and CYP2D6 genetic polymorphisms on pharmacokinetic and clinical parameters in patients receiving methadone maintenance treatment. METHODS: Opioid PhArmacoLogy (OPAL) was a clinical survey of the sociodemographic ch...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6595468/ https://ncbi.nlm.nih.gov/pubmed/30907440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13936 |
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