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Association of PON1 gene promoter DNA methylation with the risk of Clopidogrel resistance in patients with coronary artery disease

BACKGROUND AND AIMS: The failure of therapeutic response to clopidogrel in platelet inhibition, which is called clopidogrel resistance (CR), is more likely to cause cardiovascular events. We aimed to study the contribution of promoter DNA methylation of paraoxonase 1 (PON1) to the risk of clopidogre...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Lab Anal
Hauptverfasser: Su, Jia, Li, Jiyi, Yu, Qinglin, Xu, Xiaofeng, Wang, Jingqiao, Yang, Jin, Li, Xiaojing, Chen, Xiaomin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595294/
https://ncbi.nlm.nih.gov/pubmed/30891852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22867
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