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Association of GCK gene DNA methylation with the risk of clopidogrel resistance in acute coronary syndrome patients

BACKGROUNDS: Clopidogrel resistance (CR), which was manifested as the failure of platelet inhibition in clopidogrel treatment, was likely to lead to cardiovascular events. Our study was aimed to explore the contribution of DNA methylation in glucokinase (GCK) to the CR risk. METHODS: Among 36 CR and...

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Detalles Bibliográficos
Publicado en:J Clin Lab Anal
Autores principales: Su, Jia, Zheng, Nan, Li, Zhenwei, Huangfu, Ning, Mei, Li, Xu, Xiaolei, Zhang, Li, Chen, Xiaomin
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031555/
https://ncbi.nlm.nih.gov/pubmed/31605429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23040
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