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BRAF-V600E–mutated Rosai-Dorfman-Destombes disease and Langerhans cell histiocytosis with response to BRAF inhibitor

Demonstration of BRAF-V600E in Rosai-Dorfman-Destombes disease requires sensitive molecular assays and molecular-based tissue immunostain. BRAF-V600E blood testing is important for disease-monitoring BRAF-mutated histiocytosis and can guide inhibitor treatment plans.

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Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Mastropolo, Rosemarie, Close, Allison, Allen, Steven W., McClain, Kenneth L., Maurer, Scott, Picarsic, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595264/
https://ncbi.nlm.nih.gov/pubmed/31213430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000093
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