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A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening

Brucella, the agent causing brucellosis, is a major zoonotic pathogen with worldwide distribution. Brucella resides and replicates inside infected host cells in membrane-bound compartments called Brucella-containing vacuoles (BCVs). Following uptake, Brucella resides in endosomal BCVs (eBCVs) that g...

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Bibliographische Detailangaben
Veröffentlicht in:mSphere
Hauptverfasser: Casanova, Alain, Low, Shyan Huey, Québatte, Maxime, Sedzicki, Jaroslaw, Tschon, Therese, Ketterer, Maren, Smith, Kevin, Emmenlauer, Mario, Ben-Tekaya, Houchaima, Dehio, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595151/
https://ncbi.nlm.nih.gov/pubmed/31243080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00380-19
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