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Effects of biomarker diagnostic accuracy on biomarker-guided phase 2 trials

Recent advancements in genomics have attracted attention towards biomarker-guided trials. These trials aim to identify therapies that target diseases based on their genetic profile, and are especially common in cancer research. Careful incorporation of biomarkers in phase II studies is critical to t...

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Pubblicato in:Contemp Clin Trials Commun
Autori principali: Park, Jay JH., Harari, Ofir, Dron, Louis, Mills, Edward J., Thorlund, Kristian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595080/
https://ncbi.nlm.nih.gov/pubmed/31294127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100396
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