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Effects of biomarker diagnostic accuracy on biomarker-guided phase 2 trials

Recent advancements in genomics have attracted attention towards biomarker-guided trials. These trials aim to identify therapies that target diseases based on their genetic profile, and are especially common in cancer research. Careful incorporation of biomarkers in phase II studies is critical to t...

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Bibliografische gegevens
Gepubliceerd in:Contemp Clin Trials Commun
Hoofdauteurs: Park, Jay JH., Harari, Ofir, Dron, Louis, Mills, Edward J., Thorlund, Kristian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595080/
https://ncbi.nlm.nih.gov/pubmed/31294127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100396
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