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Effects of biomarker diagnostic accuracy on biomarker-guided phase 2 trials

Recent advancements in genomics have attracted attention towards biomarker-guided trials. These trials aim to identify therapies that target diseases based on their genetic profile, and are especially common in cancer research. Careful incorporation of biomarkers in phase II studies is critical to t...

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Опубликовано в: :Contemp Clin Trials Commun
Главные авторы: Park, Jay JH., Harari, Ofir, Dron, Louis, Mills, Edward J., Thorlund, Kristian
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595080/
https://ncbi.nlm.nih.gov/pubmed/31294127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100396
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