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The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation
Applying pre-steady state kinetics to an Escherichia-coli-based reconstituted translation system, we have studied how the antibiotic viomycin affects the accuracy of genetic code reading. We find that viomycin binds to translating ribosomes associated with a ternary complex (TC) consisting of elonga...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6594751/ https://ncbi.nlm.nih.gov/pubmed/31172942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46124 |
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