Genomic and transcriptional heterogeneity of multifocal hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) often presents with multiple nodules within the liver, with limited effective interventions. The high genetic heterogeneity of HCC might be the major cause of treatment failure. We aimed to characterize genomic heterogeneity, infer clonal evolution, investi...

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Bibliografske podrobnosti
izdano v:Ann Oncol
Main Authors: Xu, L X, He, M H, Dai, Z H, Yu, J, Wang, J G, Li, X C, Jiang, B B, Ke, Z F, Su, T H, Peng, Z W, Guo, Y, Chen, Z B, Chen, S L, Peng, S, Kuang, M
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594462/
https://ncbi.nlm.nih.gov/pubmed/30916311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdz103
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