Genomic and transcriptional heterogeneity of multifocal hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) often presents with multiple nodules within the liver, with limited effective interventions. The high genetic heterogeneity of HCC might be the major cause of treatment failure. We aimed to characterize genomic heterogeneity, infer clonal evolution, investi...

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Bibliografiske detaljer
Udgivet i:Ann Oncol
Main Authors: Xu, L X, He, M H, Dai, Z H, Yu, J, Wang, J G, Li, X C, Jiang, B B, Ke, Z F, Su, T H, Peng, Z W, Guo, Y, Chen, Z B, Chen, S L, Peng, S, Kuang, M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594462/
https://ncbi.nlm.nih.gov/pubmed/30916311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdz103
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