Genomic and transcriptional heterogeneity of multifocal hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) often presents with multiple nodules within the liver, with limited effective interventions. The high genetic heterogeneity of HCC might be the major cause of treatment failure. We aimed to characterize genomic heterogeneity, infer clonal evolution, investi...

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Detalhes bibliográficos
Publicado no:Ann Oncol
Main Authors: Xu, L X, He, M H, Dai, Z H, Yu, J, Wang, J G, Li, X C, Jiang, B B, Ke, Z F, Su, T H, Peng, Z W, Guo, Y, Chen, Z B, Chen, S L, Peng, S, Kuang, M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594462/
https://ncbi.nlm.nih.gov/pubmed/30916311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdz103
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