Tofacitinib in Combination With Methotrexate in Patients With Rheumatoid Arthritis: Clinical Efficacy, Radiographic, and Safety Outcomes From a Twenty‐Four–Month, Phase III Study

OBJECTIVE: Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis (RA). The phase III, 24‐month, placebo‐controlled Oral Rheumatoid Arthritis (ORAL) Scan trial was undertaken to evaluate the efficacy, including inhibition of structural progression, and safety of tofacitinib i...

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Bibliographic Details
Published in:Arthritis Rheumatol
Main Authors: van der Heijde, Désirée, Strand, Vibeke, Tanaka, Yoshiya, Keystone, Edward, Kremer, Joel, Zerbini, Cristiano A. F., Cardiel, Mario H., Cohen, Stanley, Nash, Peter, Song, Yeong‐Wook, Tegzová, Dana, Gruben, David, Wallenstein, Gene, Connell, Carol A., Fleischmann, Roy
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Rheumatoid Arthritis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593705/
https://ncbi.nlm.nih.gov/pubmed/30666826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40803
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