Tofacitinib in Combination With Methotrexate in Patients With Rheumatoid Arthritis: Clinical Efficacy, Radiographic, and Safety Outcomes From a Twenty‐Four–Month, Phase III Study

OBJECTIVE: Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis (RA). The phase III, 24‐month, placebo‐controlled Oral Rheumatoid Arthritis (ORAL) Scan trial was undertaken to evaluate the efficacy, including inhibition of structural progression, and safety of tofacitinib i...

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Veröffentlicht in:Arthritis Rheumatol
Hauptverfasser: van der Heijde, Désirée, Strand, Vibeke, Tanaka, Yoshiya, Keystone, Edward, Kremer, Joel, Zerbini, Cristiano A. F., Cardiel, Mario H., Cohen, Stanley, Nash, Peter, Song, Yeong‐Wook, Tegzová, Dana, Gruben, David, Wallenstein, Gene, Connell, Carol A., Fleischmann, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Rheumatoid Arthritis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593705/
https://ncbi.nlm.nih.gov/pubmed/30666826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40803
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