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Helix-A peptide prevents gp120-mediated neuronal loss

AIM: The human-immunodeficiency virus (HIV) envelope protein gp120 promotes synaptic damage similar to that observed in people living with HIV who have neurocognitive disorders. The neurotoxic effect of gp120 appears to occur through the α-helix motif that binds to neuronal microtubules (MTs). In th...

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Publicado en:Mol Brain
Main Authors: Avdoshina, Valeria, Taraballi, Francesca, Tasciotti, Ennio, Üren, Aykut, Mocchetti, Italo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593494/
https://ncbi.nlm.nih.gov/pubmed/31238994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0482-z
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