Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo

Multiple myeloma is a fatal plasma cell malignancy that is reliant on the bone marrow microenvironment. The bone marrow is comprised of numerous cells of mesenchymal and hemopoietic origin. Of these, macrophages have been implicated to play a role in myeloma disease progression, angiogenesis, and dr...

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Pubblicato in:Neoplasia
Autori principali: Opperman, Khatora S., Vandyke, Kate, Clark, Kimberley C., Coulter, Elizabeth A., Hewett, Duncan R., Mrozik, Krzysztof M., Schwarz, Nisha, Evdokiou, Andreas, Croucher, Peter I, Psaltis, Peter J, Noll, Jacqueline E, Zannettino, Andrew CW
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2019
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Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593350/
https://ncbi.nlm.nih.gov/pubmed/31247457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.05.006
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