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On the explicit use of experimental images in high resolution cryo-EM refinement

Single particle cryogenic electron microscopy (cryo-EM) is transforming structural biology by enabling the analysis of difficult macromolecular specimens, such as membrane proteins or large complexes with flexible elements, at near atomic resolution with an accuracy close to that of X-ray crystallog...

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Bibliographic Details
Published in:F1000Res
Main Authors: Cherfils, Jacqueline, Navaza, Jorge
Format: Artigo
Language:Inglês
Published: F1000 Research Limited 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593323/
https://ncbi.nlm.nih.gov/pubmed/31281640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.19230.2
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