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CTL-Derived Exosomes Enhance the Activation of CTLs Stimulated by Low-Affinity Peptides

Cytotoxic T cells (CTLs) bind to peptides presented by MHC I (pMHC) through T cell receptors of various affinities. Low-affinity CTLs are important for the control of intracellular pathogens and cancers; however, the mechanisms by which these lower affinity CTLs are activated and maintained are not...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wu, Shu-Wei, Li, Lei, Wang, Yan, Xiao, Zhengguo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593274/
https://ncbi.nlm.nih.gov/pubmed/31275303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01274
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