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IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8(+) T cells
An effective cytotoxic T lymphocyte (CTL) response against intracellular pathogens is generally accomplished by immense CTL expansion and activation, which can destroy infected cells. Vigorous immune responses can lead to activation of bystander CD8(+) T cells, but the contribution from antigen-spec...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5645350/ https://ncbi.nlm.nih.gov/pubmed/29042682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14000-z |
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