Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma

OBJECTIVE: We sought to determine how sex and dexrazoxane therapy influence cardiac remodelling in children with sarcoma receiving high-dose doxorubicin. METHODS: In a retrospective cohort of 85 children with sarcoma receiving high-dose doxorubicin, echocardiography measures prior to, early after (w...

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Vydáno v:Open Heart
Hlavní autoři: Narayan, Hari K, Putt, Mary E, Kosaraju, Nikitha, Paz, Alejandro, Bhatt, Shivani, Plappert, Theodore, Mercer-Rosa, Laura, Armenian, Saro H, Desai, Ami V, Womer, Richard B, Ky, Bonnie
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2019
Témata:
Heart Failure and Cardiomyopathies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593195/
https://ncbi.nlm.nih.gov/pubmed/31297226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/openhrt-2019-001025
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