Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children’s Oncology Group

BACKGROUND: Dexrazoxane protects from lower-cumulative-dose doxorubicin cardiotoxicity, but the effect of dexrazoxane in children with sarcoma treated with higher-cumulative-dose doxorubicin is unknown. METHODS: We evaluated children with osteosarcoma (OS) on two Children’s Oncology Group trials wit...

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Detalhes bibliográficos
Publicado no:Cardiooncology
Main Authors: Kopp, Lisa M., Womer, Richard B., Schwartz, Cindy L., Ebb, David H., Franco, Vivian I., Hall, David, Barkauskas, Donald A., Krailo, Mark D., Grier, Holcombe E., Meyers, Paul A., Wexler, Leonard H., Marina, Neyssa M., Janeway, Katherine A., Gorlick, Richard, Bernstein, Mark L., Lipshultz, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048050/
https://ncbi.nlm.nih.gov/pubmed/32154021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40959-019-0050-9
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