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Proniosomal gel for transdermal delivery of lornoxicam: optimization using factorial design and in vivo evaluation in rats

OBJECTIVE: Clinical utility of lornoxicam in oral therapy is primarily restricted by the low solubility and gastric adverse effects. This study evaluated the prospective of optimized proniosomal gel to improve the clinical efficacy of lornoxicam and compare with oral therapy. METHODS: Proniosomes we...

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Detalhes bibliográficos
Publicado no:Daru
Main Authors: Shah, Hiral, Nair, Anroop B., Shah, Jigar, Bharadia, Praful, Al-Dhubiab, Bandar E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593013/
https://ncbi.nlm.nih.gov/pubmed/30701460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40199-019-00242-x
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