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Proniosomal gel for transdermal delivery of lornoxicam: optimization using factorial design and in vivo evaluation in rats

OBJECTIVE: Clinical utility of lornoxicam in oral therapy is primarily restricted by the low solubility and gastric adverse effects. This study evaluated the prospective of optimized proniosomal gel to improve the clinical efficacy of lornoxicam and compare with oral therapy. METHODS: Proniosomes we...

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Bibliografische gegevens
Gepubliceerd in:Daru
Hoofdauteurs: Shah, Hiral, Nair, Anroop B., Shah, Jigar, Bharadia, Praful, Al-Dhubiab, Bandar E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593013/
https://ncbi.nlm.nih.gov/pubmed/30701460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40199-019-00242-x
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