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Proniosomal gel for transdermal delivery of lornoxicam: optimization using factorial design and in vivo evaluation in rats
OBJECTIVE: Clinical utility of lornoxicam in oral therapy is primarily restricted by the low solubility and gastric adverse effects. This study evaluated the prospective of optimized proniosomal gel to improve the clinical efficacy of lornoxicam and compare with oral therapy. METHODS: Proniosomes we...
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| Publicat a: | Daru |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer International Publishing
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6593013/ https://ncbi.nlm.nih.gov/pubmed/30701460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40199-019-00242-x |
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