Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis

The brain is a major site of relapse for several cancers, yet deciphering the mechanisms of brain metastasis remains a challenge because of the complexity of the brain tumor microenvironment (TME). To define the molecular landscape of brain metastasis from intact tissue in vivo, we employ an RNA-seq...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Wingrove, Emily, Liu, Zongzhi Z., Patel, Kiran D., Arnal-Estapé, Anna, Cai, Wesley L., Melnick, Mary-Ann, Politi, Katerina, Monteiro, Cátia, Zhu, Lucía, Valiente, Manuel, Kluger, Harriet M., Chiang, Veronica L., Nguyen, Don X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592283/
https://ncbi.nlm.nih.gov/pubmed/31018140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.085
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