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Concurrent Inhibition of Vesicular Monoamine Transporter 2 Does Not Protect Against 3,4-Methylenedioxymethamphetamine (Ecstasy) Induced Neurotoxicity

3, 4-Methylenedioxymethamphetamine (MDMA) is a hallucinogenic amphetamine derivative. The acute effects of MDMA are hyperthermia, hyperactivity, and behavioral changes, followed by long-term serotonergic neurotoxicity in rats and primates. However, the underlying mechanisms of MDMA neurotoxicity rem...

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Publicado en:Toxicol Sci
Autores principales: Cholanians, Aram B, Phan, Andy V, Lau, Serrine S, Monks, Terrence J
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592187/
https://ncbi.nlm.nih.gov/pubmed/30923810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz085
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