Hepatic Hippo signaling inhibits pro-tumoral microenvironment to suppress hepatocellular carcinoma

OBJECTIVE: Hippo signaling is a recently identified major oncosuppressive pathway that plays critical roles in inhibiting hepatocyte proliferation, survival and hepatocellular carcinoma (HCC) formation. Hippo kinase (Mst1 and Mst2) inhibits HCC proliferation by suppressing Yap/Taz transcription acti...

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Publicado en:Gut
Autores principales: Kim, Wantae, Khan, Sanjoy Kumar, Liu, Yuchen, Xu, Ruoshi, Park, Ogyi, He, Yong, Cha, Boksik, Gao, Bin, Yang, Yingzi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592016/
https://ncbi.nlm.nih.gov/pubmed/28866620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-314061
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