Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq)

BACKGROUND: Comprehensive analysis of the tissue of origin of plasma cell-free DNA (cfDNA) remains insufficient. A genome-scale DNA methylation method for this analysis is of both biological and clinical interest. METHODS: We used the methylated CpG tandem amplification and sequencing (MCTA-Seq), wh...

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Publicat a:Clin Epigenetics
Autors principals: Liu, Xiaomeng, Ren, Jie, Luo, Nan, Guo, Huahu, Zheng, Yuxuan, Li, Jingyi, Tang, Fuchou, Wen, Lu, Peng, Jirun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591962/
https://ncbi.nlm.nih.gov/pubmed/31234922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0689-y
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