Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

BACKGROUND: Ethanol withdrawal (EtOHW) anxiety is a crucial risk factor for alcoholic relapse. The neuropeptide nociceptin/orphanin FQ (N/OFQ) acts upon its receptor (NOP) to antagonize corticotropin-releasing factor (CRF) and elicit anxiolytic actions. Semen Ziziphi Spinosae (SZS), a prototypical h...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Li, Li Bo, Kim, Young Woo, Wang, Yu Hua, Bai, Li, Zhu, Xiao Dong, Zhao, Zheng Lin, Lee, Chul Won, Jiao, Yu, Wu, Tong, Cai, Zhen Zhen, Kim, Sang Chan, An, Won G., Yang, Chae Ha, Cui, Guang Cheng, Zhao, Rong Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591875/
https://ncbi.nlm.nih.gov/pubmed/31234859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2546-0
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