Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

BACKGROUND: Ethanol withdrawal (EtOHW) anxiety is a crucial risk factor for alcoholic relapse. The neuropeptide nociceptin/orphanin FQ (N/OFQ) acts upon its receptor (NOP) to antagonize corticotropin-releasing factor (CRF) and elicit anxiolytic actions. Semen Ziziphi Spinosae (SZS), a prototypical h...

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Detalles Bibliográficos
Publicado en:BMC Complement Altern Med
Main Authors: Li, Li Bo, Kim, Young Woo, Wang, Yu Hua, Bai, Li, Zhu, Xiao Dong, Zhao, Zheng Lin, Lee, Chul Won, Jiao, Yu, Wu, Tong, Cai, Zhen Zhen, Kim, Sang Chan, An, Won G., Yang, Chae Ha, Cui, Guang Cheng, Zhao, Rong Jie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591875/
https://ncbi.nlm.nih.gov/pubmed/31234859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2546-0
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