Aqueous Extract of Semen Ziziphi Spinosae Exerts Anxiolytic Effects during Nicotine Withdrawal via Improvement of Amygdaloid CRF/CRF1R Signaling

Anxiety during nicotine withdrawal (NicW) is a key risk factor for smoking relapse. Semen Ziziphi Spinosae (SZS), which is a prototypical hypnotic-sedative herb in Oriental medicine, has been clinically used to treat insomnia and general anxiety disorders for thousands of years. Thus, the present st...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Gu, Changhong, Zhao, ZhengLin, Zhu, Xiaodong, Wu, Tong, Lee, Bong Hyo, Jiao, Yu, Lee, Chul Won, Jung, Dae Hwa, Yang, Chae Ha, Zhao, Rongjie, Kim, Sang Chan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139233/
https://ncbi.nlm.nih.gov/pubmed/30245730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2419183
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