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Isolation of Phage Lysins That Effectively Kill Pseudomonas aeruginosa in Mouse Models of Lung and Skin Infection

Multidrug resistance (MDR) is rapidly increasing in prevalence among isolates of the opportunistic pathogen Pseudomonas aeruginosa, leaving few treatment options. Phage lysins are cell wall hydrolases that have a demonstrated therapeutic potential against Gram-positive pathogens; however, the outer...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Raz, Assaf, Serrano, Anna, Hernandez, Anaise, Euler, Chad W., Fischetti, Vincent A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591642/
https://ncbi.nlm.nih.gov/pubmed/31010858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00024-19
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