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Isolation of Phage Lysins That Effectively Kill Pseudomonas aeruginosa in Mouse Models of Lung and Skin Infection

Multidrug resistance (MDR) is rapidly increasing in prevalence among isolates of the opportunistic pathogen Pseudomonas aeruginosa, leaving few treatment options. Phage lysins are cell wall hydrolases that have a demonstrated therapeutic potential against Gram-positive pathogens; however, the outer...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Raz, Assaf, Serrano, Anna, Hernandez, Anaise, Euler, Chad W., Fischetti, Vincent A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591642/
https://ncbi.nlm.nih.gov/pubmed/31010858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00024-19
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