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Errors of Fixed QT Heart Rate Corrections Used in the Assessment of Drug-Induced QTc Changes

The accuracy of studies of drug-induced QTc changes depends, among others, on the accuracy of heart rate correction of QT interval. It has been recognized that when a drug leads to substantial heart rate changes, fixed universal corrections cannot be used and that alternative methods such as subject...

詳細記述

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書誌詳細
出版年:Front Physiol
主要な著者: Hnatkova, Katerina, Vicente, Jose, Johannesen, Lars, Garnett, Christine, Stockbridge, Norman, Malik, Marek
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591442/
https://ncbi.nlm.nih.gov/pubmed/31275152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00635
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