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Durability of cell line xenograft resection models to interrogate tumor micro-environment targeting agents
Angiogenesis is a key tumor microenvironment (TME) event underpinning tumor growth and metastasis. Nevertheless, the relatively poor performance of anti-angiogenic therapies in clinical trials compared to pre-clinical studies implies that classical subcutaneous xenograft models have limited predicti...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591410/ https://ncbi.nlm.nih.gov/pubmed/31235775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45444-0 |
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