The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload

Left ventricular (LV) dilatation is a key step in transition to heart failure (HF) in response to pressure overload. Cardiac extracellular matrix (ECM) contains fibrillar collagens and proteoglycans, important for maintaining tissue integrity. Alterations in collagen production and cross-linking are...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mohammadzadeh, Naiyereh, Lunde, Ida G., Andenæs, Kine, Strand, Mari E., Aronsen, Jan Magnus, Skrbic, Biljana, Marstein, Henriette S., Bandlien, Caroline, Nygård, Ståle, Gorham, Joshua, Sjaastad, Ivar, Chakravarti, Shukti, Christensen, Geir, Engebretsen, Kristin V. T., Tønnessen, Theis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591256/
https://ncbi.nlm.nih.gov/pubmed/31235849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45651-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados