Protective effects of the Francisella tularensis ΔpdpC mutant against its virulent parental strain SCHU P9 in Cynomolgus macaques

Tularemia is a severe infectious zoonotic disease caused by Francisella tularensis. Although F. tularensis is considered to be a potential biological weapon due to its high infectivity and mortality rate, no vaccine has been currently licensed. Recently, we reported that F. tularensis SCHU P9 derive...

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Udgivet i:Sci Rep
Main Authors: Tian, Deyu, Uda, Akihiko, Ami, Yasushi, Hotta, Akitoyo, Park, Eun-sil, Nagata, Noriyo, Iwata-Yoshikawa, Naoko, Yamada, Akio, Hirayama, Kazuhiro, Miura, Kozue, Koyama, Yuki, Azaki, Mika, Morikawa, Shigeru
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591246/
https://ncbi.nlm.nih.gov/pubmed/31235714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45412-8
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