QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer’s Disease

Alzheimer’s disease is one of the most common neurodegenerative disorders in elder population. The β-site amyloid cleavage enzyme 1 (BACE1) is the major constituent of amyloid plaques and plays a central role in this brain pathogenesis, thus it constitutes an auspicious pharmacological target for it...

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Foilsithe in:Sci Rep
Main Authors: Ponzoni, Ignacio, Sebastián-Pérez, Víctor, Martínez, María J., Roca, Carlos, De la Cruz Pérez, Carlos, Cravero, Fiorella, Vazquez, Gustavo E., Páez, Juan A., Díaz, Mónica F., Campillo, Nuria E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591229/
https://ncbi.nlm.nih.gov/pubmed/31235739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45522-3
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