Mechanisms of human FoxP3(+) T(reg) cell development and function in health and disease

Regulatory T (T(reg)) cells represent an essential component of peripheral tolerance. Given their potently immunosuppressive functions that is orchestrated by the lineage‐defining transcription factor forkhead box protein 3 (FoxP3), clinical modulation of these cells in autoimmunity and cancer is a...

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Bibliographic Details
Published in:Clin Exp Immunol
Main Authors: Attias, M., Al‐Aubodah, T., Piccirillo, C. A.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Review Series: Regulatory T Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591147/
https://ncbi.nlm.nih.gov/pubmed/30864147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13290
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