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Comprehensive quantitation of RNA-protein interaction dynamics by orthogonal organic phase separation (OOPS)
Existing high-throughput methods to identify RNA-binding proteins (RBPs) involving capture of polyadenylated RNAs can not recover proteins that interact with non-adenylated RNAs, including lncRNA, pre-mRNA and bacterial RNAs. We present orthogonal organic phase separation (OOPS) which does not requi...
שמור ב:
| הוצא לאור ב: | Nat Biotechnol |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591131/ https://ncbi.nlm.nih.gov/pubmed/30607034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-018-0001-2 |
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