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Precision medicine in Type 2 diabetes: Clinical markers of insulin resistance are associated with altered short and long-term glycemic response to DPP4-inhibitor therapy

OBJECTIVE: A ‘precision’ approach to type 2 diabetes therapy would aim to target treatment according to patient characteristics. We examined if measures of insulin resistance and secretion were associated with glycemic response to DPP4-inhibitor therapy. RESEARCH DESIGN AND METHODS: We evaluated whe...

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Foilsithe in:Diabetes Care
Main Authors: Dennis, John M., Shields, Beverley M., Hill, Anita V., Knight, Bridget A., McDonald, Timothy J., Rogers, Lauren R., Weedon, Michael N., Henley, William E., Sattar, Naveed A., Holman, Rury R., Pearson, Ewan R., Hattersley, Andrew T., Jones, Angus G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591121/
https://ncbi.nlm.nih.gov/pubmed/29386249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc17-1827
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