Sex and BMI alter the benefits and risks of sulfonylureas and thiazolidinediones in type 2 diabetes: A framework for evaluating stratification using routine clinical and individual trial data

OBJECTIVE: The choice of therapy for type 2 diabetes after metformin is guided by overall estimates of glycemic response and side-effects seen in large cohorts. A stratified approach to therapy would aim to improve on this by identifying subgroups of patients whose glycaemic response or risk of side...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Dennis, John M, Henley, William E, Weedon, Michael N, Lonergan, Mike, Rodgers, Lauren R, Jones, Angus G, Hamilton, William T, Sattar, Naveed, Janmohamed, Salim, Holman, Rury R, Pearson, Ewan R, Shields, Beverley M, Hattersley, Andrew T
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591127/
https://ncbi.nlm.nih.gov/pubmed/30072404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc18-0344
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