Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination

Rapidly evolving RNA viruses, such as the GII.4 strain of human norovirus (HuNoV), and their vaccines elicit complex serological responses associated with previous exposure. Specific correlates of protection, moreover, remain poorly understood. Here, we report the GII.4-serological antibody repertoi...

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Détails bibliographiques
Publié dans:Immunity
Auteurs principaux: Lindesmith, Lisa C., McDaniel, Jonathan R., Changela, Anita, Verardi, Raffaello, Kerr, Scott A., Costantini, Veronica, Brewer-Jensen, Paul D., Mallory, Michael L., Voss, William N., Boutz, Daniel R., Blazeck, John J., Ippolito, Gregory C., Vinje, Jan, Kwong, Peter D., Georgiou, George, Baric, Ralph S.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591005/
https://ncbi.nlm.nih.gov/pubmed/31216462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.05.007
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