Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination

Rapidly evolving RNA viruses, such as the GII.4 strain of human norovirus (HuNoV), and their vaccines elicit complex serological responses associated with previous exposure. Specific correlates of protection, moreover, remain poorly understood. Here, we report the GII.4-serological antibody repertoi...

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Udgivet i:Immunity
Main Authors: Lindesmith, Lisa C., McDaniel, Jonathan R., Changela, Anita, Verardi, Raffaello, Kerr, Scott A., Costantini, Veronica, Brewer-Jensen, Paul D., Mallory, Michael L., Voss, William N., Boutz, Daniel R., Blazeck, John J., Ippolito, Gregory C., Vinje, Jan, Kwong, Peter D., Georgiou, George, Baric, Ralph S.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591005/
https://ncbi.nlm.nih.gov/pubmed/31216462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.05.007
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